Mesangial cell inflammation. IGA nephropathy occurs when inflammation initially, when the disease, kidney mesangial cells in patients with inflammatory damage will be stimulated to produce inflammatory cytokines, resulting in a large number of immune complex precipitation in the patient's kidneys and eventually cause disease produced .
Mesangial area of a large number of immune complexes precipitated material. IGA nephropathy in vivo mesangial area a large number of patients with immune complexes precipitated material, wherein the primary immune complexes to glomerular mesangial cells IGA and IGA nephropathy in patients with high affinity, after a combination of both can lead to kidney inherent cells phenotypic transformation occurs and cause disease.
Infection. Colds, tonsillitis, fever appears to the naked eye or urine occult blood, recurrent infection factors, the majority of patients with hematuria only exception to the hospital in the body.
Genetic. IGA groups on the incidence of kidney patients to investigate the phenomenon of familial aggregation part IGA nephropathy occurs, which shows that a genetic predisposition to a certain extent IGA nephropathy.
For patients suffering from IGA nephropathy, usually should pay attention to proper rest and avoid strenuous activity, proper workout in stable condition. Furthermore, patients need to enhance disease resistance, to avoid the cold, reducing the chance of infection. In the diet, IGA patients should be light-based diet, eat more vegetables, fruit and high-quality protein foods, fasting spicy, and mildew products and pickled products, avoid alcohol.
Above will introduce you to the reasons iga nephropathy formation, if you want to know more information, you can leave a message to igacure@gmail.com, we will promptly get back to you.
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