In medicine there are many ways to treat chronic nephritis, then let's take a look at these treatments together. After all, this is still a lot of help to us.
1. Active control of hypertension and reduced urinary protein
Hypertension and urinary protein is an important factor in accelerating glomerulosclerosis and promoting deterioration of renal function. Active control of hypertension and reduction of urinary protein are two important links. Chronic nephritis often sodium and water retention caused by capacity-dependent hypertension, so patients with hypertension should be limited salt (NaCl <6g / d); optional thiazide diuretics, such as hydrochlorothiazide.
Ccr <30ml / min, the thiazide ineffective should use the loop diuretics, but generally should not be too much, long-term use. ACEI or ARB in addition to lower blood pressure, but also reduce the urinary protein and delay the deterioration of renal function of renal protection, chronic nephritis treatment of hypertension and / or reduce urinary protein drug of choice. Usually to achieve the purpose of reducing urinary protein, the application dose often need higher than the conventional antihypertensive dose. Renal insufficiency in patients with ACEI or ARB to prevent hyperkalemia, serum creatinine greater than 264μmol / L (3mg / d1) must be closely monitored serum creatinine, serum potassium, to prevent side effects.
In addition to the above methods of controlling hypertension, we can also combine the above methods together, or choose some β-blockers for treatment.
2. Limit the amount of protein and phosphorus in food
Renal insufficiency azotemia patients should limit the amount of protein and phosphorus, the use of high-quality low-protein diet or add essential amino acids or α-keto acid.
3. Glucocorticoids and cytotoxic drugs
In view of chronic nephritis, including a variety of diseases, so whether the application of drugs, should be treated differently. But the patient's normal renal function or only mildly damaged, normal renal volume, pathological type of light (such as mild mesangial proliferative glomerulonephritis, early membranous nephropathy, etc.), more urine protein, such as no contravention can try, invalid Gradually withdraw.
4. Anticoagulant, fibrinolytic and antiplatelet depolymerization drugs
Such drugs can inhibit fibrin formation, platelet aggregation, reduce complement activity, but the effect is not sure.
5. To avoid aggravating the factors of kidney damage
Chronic nephritis patients, in the usual life, but also pay more attention to life washed, to avoid some of the infection or fatigue, which may lead to deterioration of renal function.
Drug treatment of chronic nephritis
Chronic glomerulonephritis is what we usually refer to chronic nephritis, it refers to the different causes of different pathology constitute a group of primary glomerular disease, manifested as edema, hypertension, proteinuria, hematuria and varying degrees Of renal dysfunction. It is characterized by long course of disease (more than a year), the disease progress is slow, the symptoms can be light and heavy, and ultimately into chronic renal failure. The rate of progression of the disease depends, of course, on the type of pathology, but the correct treatment and maintenance also plays a vital role. Therefore, we must take a comprehensive prevention and treatment of chronic nephritis, to slow down the deterioration of renal function, improve or reduce clinical symptoms, prevention and treatment of serious complications, not blindly to eliminate hematuria, proteinuria as the goal. Here focuses on the treatment of chronic nephritis.
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