A glomerular filtration rate (GFR)
What is the rate of glomerular filtration, GFR what meaning? Indeed, the rate of glomerular filtration is an important indicator of glomerular filtration function. For the glomerular filtration rate can not be measured directly, must use a kind of substance, a substance by measuring the clearance rate indirectly reflects the rate of glomerular filtration. Such as the rate of glomerular filtration decreased then the cells are inherent kidney damage, leading to nephron glomerular filtration rate.
What is nitrogen of serum urea? The nitrogen of serum urea have an effect on renal function do? In fact, blood urea is the end product of protein metabolism, the main excretion of urea nitrogen in the body's blood by the kidneys, a small part can be excreted by sweat. It is only when the rate of glomerular filtration is reduced to the original 1/2, urea will increase, so that the index measuring urea nitrogen is little sensitive to reflect the rate of glomerular filtration.
Nitrogen test of urea will be affected by diet, infections, high fever and other effects. But because nitrogen concentrations of plasma urea over the course of chronic kidney disease, prognosis status and observation has significant significance, so that the plasma determination of nitrogen urea is Still one of the main biochemical examinations of kidney disease.
Serum creatinine is produced by muscle metabolism in blood creatinine, serum creatinine becomes. When the rate of glomerular filtration decreased to 1/3 of the original, serum creatinine increases. General increase in serum creatinine is common in chronic renal failure, renal failure, severe renal disease uremia.
Uric acid is the product of the purine metabolism, uric acid body in one third of the food produced by its two-thirds, mainly excreted by the late kidneys. Determination of the use of uric acid in the early diagnosis of kidney disease, when uric acid was significantly higher, common in acute and chronic nephritis, other renal diseases in the stage such as renal tuberculosis, Pyelonephritis, hydronephrosis, also the concentration of visible uric acid.
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