2014年11月27日星期四

Therapeutic and prognostic IgA nephritis

1, a protein supply. Dietary treatment of chronic nephritis should be determined according to the degree of renal dysfunction protein intake, if longer duration, renal damage is not serious, food protein is not strictly limited, but not more than 1 gram per kilogram of body weight per day, high-quality protein to reach more than 50%.
2, due to the limitations of the protein part of the patient, the supply of energy to carbohydrate and fat as the main source of energy supply, as the labor intensity may be. The Breakers, adult daily supply of 126 kJ to 147 kJ (30 kcal to 35 kcal) / kg body weight. To meet the needs of the patient and the activities.
3, the control sodium intake. Severe edema and hypertension, to control the amount of sodium in the following 2 g / day, even given salt-free diet, generally low-salt appropriate.
Prognosis:
The disease may have spontaneous remission, or about 4% to 20%. Each year, about 1% to 2% of patients with end-stage renal failure to enter. Statistical life-table analysis showed 10-year graft survival was 80% to 90%. Eventually developed into uremia estimate about 35%. The rest is sustained hematuria or proteinuria. Poor prognosis factors: namely the onset of renal insufficiency, proteinuria than 1.5g / d, high blood pressure and no gross hematuria; biopsy glomerular sclerosis, interstitial fibrosis, glomerular capillary was violations, diffuse proliferative and diffuse crescent formation.

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