We know iga nephropathy is a very common disease, and the incidence is relatively high in the country, especially in recent years, iga nephropathy continues with the reasons for the onset of infection, causing a lot of people want to understand the cause of iga nephropathy, then life relatively easy to factors iga nephropathy, what does? take a look.
The exact pathogenesis of IgA nephropathy is not yet entirely clear, a variety of factors and pathogenesis. Current consensus view is that the case of immune complexes iga nephropathy induced glomerular disease. Factor in life are prone to iga nephropathy is common in:
1, infection. This is mainly due to the common cold, inflammation of the urinary system caused by conditions such as an emotional of complications. Damage to the kidneys, causing IGA nephropathy. Life is easier factors iga nephropathy
2, the genetic factors. While modern medicine has not proven IGA nephropathy is a genetic disease, but not difficult to find IGA nephropathy patients now appear familial aggregation phenomenon, which still shows IGA nephropathy is associated with genetic.
3, the main body of abnormal precipitation IGA participate pathogenic immune complexes. This is the region of the patient mesangial precipitate a large amount of immune complexes, after a series of reactions leading to changes in the cells of the kidney damage inherent to lesions.
It is noteworthy that the diagnosis of IgA nephropathy in renal biopsy must have, must have immunofluorescence or immunohistochemical results support. Its diagnostic features are: light microscopy common diffuse mesangial proliferative or focal segmental glomerulonephritis; diagnostic immunofluorescence visible mesangial IgA immune complex deposition or IgA-based, which is IgA nephropathy flag.
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